Saranya Wyles, M.D., Ph.D. is the Director at Mayo Clinic Regenerative Dermatology and Skin Longevity Laboratory. Her research has pioneered the definition of skin cellular senescence, or cell aging, and skin-specific senescence gene sets, trademarked as SenSkin, marking the first comprehensive principles of skin aging, with findings published in Nature Aging and Aging Cell.
She is responsible for the planning and execution of the NIH-funded laboratory’s multifaceted preclinical and clinical programs focused on regenerative biotherapies for inflammatory and age-related skin conditions. Her primary objective as director is to design new 3D bioprinted skin aging and skin disease models for preclinical testing in alignment with U.S. FDA initiative.
Dr. Wyles holds two U.S. patents on methods and materials to reduce scar formation and additional U.S. patent-pending technologies for 3D skin bioprinting.
At Mayo Clinic, she also serves as Associate Education Director at Center for Regenerative Biotherapeutics where she is responsible for developing new training platforms in regenerative sciences for the next-generation healthcare workforce. Before joining Mayo Clinic, Dr. Wyles pursued a research fellowship at the Harvard Stem Cell Institute.
Dr. Wyles received her M.D.-Ph.D. from Mayo Clinic.
She is a board-certified dermatologist and completed a Mayo Scholar fellowship at Wake Forest School of Medicine and King’s College London.
She has earned a national and international reputation for her diverse and unique expertise via her journal publications and has received several scientific achievement awards, including NIH National Institute on Aging Butler-Williams Scholarship.
Her work was also featured on NBC Today’s Show segment, What are zombie cells, and can they slow aging?